Protein Modification Reagents
Medchemexpress LLC N-(2-(4-(3,5-dioxo-1,2,4-triazolidin-4-yl)-2-methoxyphenoxy)ethyl)-4,7,10,13-tetraoxahexadec-15-ynami | 99.3% | 508.52 g/mol | C23H32N4O9 | 25 MG
PTAD-PEG4-alkyne is a heterobifunctional linker containing a PTAD tyrosine-reactive moiety and a terminal alkyne separated by a four-unit PEG spacer. It is used for bioconjugation and antibody-drug conjugate synthesis to enable tyrosine-selective labeling and alkyne-based click chemistry.
- Cleavable PEG4 spacer for improved solubility and flexibility.
- Terminal alkyne for copper-catalyzed azide-alkyne cycloaddition.
- PTAD moiety enables tyrosine-selective conjugation.
- High purity (99.26%) suitable for research use.
- Soluble in DMSO (125 mg/mL); powder stable at -20°C.
Worthington Biochemical Corporation COLLAGENASE TYPE 1 FLTRD 1GR
Collagenase, Type 1 (Code: CLS-1), which is filtered through a 0.22 micron membrane and lyophilized in vials.
Sigma Aldrich Fine Chemicals Biosciences Trypsin Sequencing Grade, 4 x 25 ug
Trypsin Sequencing Grade is used to to digest proteins in solution, in gels or on blotting membranes.The enzyme is used for protein-structure elucidation, tryptic mapping, fingerprinting, sequence analysis, and translocation studies. Trypsin Sequencing Grade generates glycopeptides from purified glycoproteins and is suited for the digestion of proteins in polyacrylamide gels.
Sigma Aldrich Fine Chemicals Biosciences Collagenase P from Clostridium histolyticum |
Collagenase P from Clostridium histolyticum |
Medchemexpress LLC Diketone-PEG4-PFP ester | 2353409-84-2 | ≥97.0% | 647.58 | 25 MG
Diketone-PEG4-PFP ester is a PROTAC linker, specifically a PEG-based PROTAC linker, designed for use in the synthesis of PROTACs. PROTACs themselves are compounds that contain two distinct ligands connected by a linker; one ligand targets an E3 ubiquitin ligase, and the other targets the protein intended for degradation. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade specific target proteins.
- Diketone-PEG4-PFP ester is a PEG-based PROTAC linker.
- It is used in the synthesis of PROTACs.
- PROTACs utilize the ubiquitin-proteasome system for selective degradation of target proteins.
Worthington Biochemical Corporation Trypsin, 1g
Supplied as a dialyzed and lyophilized powder. Store at 2-8°C. Protect from moisture.
Cayman Chemical dPE-PEG 2000-DBCO 10mg
An internal standard for the quantification of betahistine by GC- or LC-MS
Sigma Aldrich Fine Chemicals Biosciences Endoproteinase Glu-C from Staphylococcus aureus V8 suitable for protein sequencing, lyophilized powder | 66676-43-5 | MFCD01324998 | 50UG
Endoproteinase Glu-C from Staphylococcus aureus V8 suitable for protein sequencing, lyophilized powder | 66676-43-5 | MFCD01324998 | 50UG
Medchemexpress LLC Tri(amino-PEG4-amide)-amine | 2523025-41-2 | 95.0% | C39H81N7O15 | 100 MG
Tri(Amino-PEG4-amide)-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. These PROTACs consist of two different ligands connected by a linker, one targeting an E3 ubiquitin ligase and the other a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective protein degradation. This product is for research use only.
- Used in the synthesis of PROTACs
- PROTACs contain two different ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets a specific protein
- Exploits the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
- For research use only
Medchemexpress LLC DBCO-PEG1-NHS ester | 2228857-34-7 | 95.0% | C28H27N3O7 | 50 MG
DBCO-PEG1-NHS ester is a PEG-based PROTAC linker. It is also a click chemistry reagent that contains a DBCO group, enabling strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group for SPAAC
- Applicable in cancer research and targeted therapy
Medchemexpress LLC Mal-amido-PEG8-TFP ester | 1924596-31-5 | C32H44F4N2O13 | 250 MG
Mal-amido-PEG8-TFP ester is a PEG-based PROTAC linker. It is utilized in the synthesis of PROTACs, which are molecules designed to exploit the intracellular ubiquitin-proteasome system for the selective degradation of target proteins. PROTACs achieve this by containing two different ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Designed for selective degradation of target proteins
Medchemexpress LLC Rhodamine B PEG2-NH2 | 95.3% | 566.13 | 25 MG
Rhodamine B PEG2-NH2 is a PEG-based PROTAC linker. It is used in the synthesis of PROTACs, which contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein. These PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. For research use only.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates targeted protein degradation